It has been known for centuries that turmeric has anti-inflammatory action.Old-fashioned treatments are safe in most cases, but have generally not been the subject of extensive medical research and are therefore ignored because their active components are not clearly defined.Fortunately, the same cannot be said of turmeric, the component of turmeric that gives it its anti-inflammatory property.Identified more than 100 years ago, curcumin has been the subject of a number of studies under the auspices of the National Institutes of Health (NIH), the United States Medical Research Agency.The NIH is funded by thousands of scientists from universities and research centers across the Americas and around the globe.Curcumin is the most powerful natural anti-inflammatoryHundreds of studies have shown that it has comparable effects to strong drugs (eg ibuprofen, hydrocortisone, phenylbutazone), but without their negative effects on the human body.The anti-inflammatory effect of curcumin is due to the ability of this polyphenol to inhibit the activity of enzymes that play an important role in producing and maintaining chronic inflammation.Curcumin has been shown to regulate many factors, such as cytokines, protein kinases, adhesion molecules, redox molecules and inflammation-causing enzymes.The inflammatory process has been shown to play a major role in most chronic diseases, such as neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic.Numerous articles published both on the NIH website and by other researchers provide evidence in favor of the role that curcumin plays in the prevention and treatment of various chronic pro-inflammatory diseases.All these features, combined with pharmacological safety and low cost, make turmeric a very interesting agent to explore.Curcumin has shown therapeutic potential in various chronic diseases, including inflammation, which is known to play a major role in joint disease, including Alzheimer's (AD), Parkinson's, multiple sclerosis, epilepsy, stroke, cardiovascular disease, cancer. allergies, asthma, bronchitis, colitis, renal ischemia, psoriasis, diabetes, obesity, depression, fatigue and AIDS.Curcumin and joint ailmentsArthritis is a pathological condition characterized by joint inflammation, a phenomenon usually accompanied variably by the following signs: pain, swelling, high local temperature, redness of the periarticular skin and limiting the function of the joint involved.There are over 100 types of arthritis.The 3 most common subcategories are: gout, osteoarthritis (OS), rheumatoid arthritis (RA)Gout occurs in response to the presence of sodium urate monohydrate crystals in the joints, bones and soft tissues and is treated with nonsteroidal anti-inflammatory agents (NSAIDs), oral or intravenous colchicine and intravenous or intra-articular glucocorticoids.All have been shown to be effective in stopping acute gout attacks, but all have severe side effects.Osteoarthritis (OA), the second most widespread type of arthritis in the world, is the result of joint cartilage damage, induced by a combination of genetic, metabolic, biochemical and biomechanical factors.OA is normally treated with analgesics such as acetaminophen (paracetamol) or opioids (eg tramadol), nonsteroidal anti-inflammatory agents (NSAIDs), but also with intra-articular therapies (glucocorticoids and hyaluronic acid).Rheumatoid arthritis (RA), the third most common in the world, is a chronic proinflammatory disease characterized by hyperplasia of synovial fibroblast cells.Like many other autoimmune diseases, arthritis is much more common in the Western world than in other parts of the globe.Although the reasons for this "predilection" are not yet well understood, it is known that lifestyle plays an important role.AR is much more common in women (75% vs. 25%), suggesting the role of hormones in the etiology of the disease.The role of inflammatory cytokines (TNF, IL-1, IL-6) and chemokines, inflammatory enzymes (COX-2, 5-LOX, and MMP-9) and adhesion molecules is well documented in the pathogenesis of arthritis.It has been shown that almost all mediators of inflammation related to arthritis are controlled by the transcription factor NF-κB.Because arthritis treatments are ineffective, produce substantial side effects, and are relatively expensive, natural products, which do not have any of these disadvantages, offer new treatment options.According to a large number of studies, curcumin has a great potential to help treat arthritis due to its very strong anti-inflammatory effect because it inhibits inflammatory cytokines, inflammatory enzymes (COX-2 and 5-LOX), neutral matrix metalloproteinases (MMPs) and influences TNF. -α, actions that reduce pain and increase mobility in joint diseases.More information can be found here.Clinical studies indicate the need to administer approximately 1 gram of curcumin daily in the treatment of joint diseases, accompanied by black pepper extract without which it is not absorbed into the body.Given that the simple plant, turmeric, has a concentration of only 3-5% curcumin, a quantity of 20-35 g of spice should be consumed daily, which is almost impossible.That is why it is recommended to use direct turmeric extract, which contains a percentage of 95% curcuminoid (active substance) - Curcumin 95. More information about turmeric spice and curcumin can be found here.A very important feature that must be taken into account when taking curcumin is its very poor absorption into the blood.Taken as a whole, curcumin reaches an insignificant proportion in the tissues.In order to be absorbed by the human body, it is necessary to administer concomitantly with piperine - black pepper extract.IANA LIFE PRODUCT Curcumin 95% with BioperineIANA LIFE Curcumin 95 capsules contain curcumin with a concentration of 95% and Bioperine (black pepper extract), which increases the bioavailability of the active substance by up to 2000% and without which curcumin is absorbed in the body in insignificant amounts.It is the only curcumin 95 product present on the Romanian market that has the content of black pepper extract.Content / capsule: 350 mg curcumin (standardized curcumin extract 95% curcuminoids), 5 mg Bioperine (standardized black pepper extract 95% piperine), 45 mg anti-caking substance (microcrystalline cellulose and vegetable magnesium stearate)Country of origin - India, CroatiaMethod of administration: 1-3 capsules / day (during the meal) or according to the recommendation of the specialist consultant.Contraindications: Not recommended for people with thyroid disease, pregnant women and nursing mothers.People on medication should consult their doctor before administration.Iana Life Curcumin 95 capsules contain Bioperine® - 95% black pepper piperine extract.Bioperine® is a patented product, tested and supported by numerous studies for its ability to increase the bioavailability of nutritional compounds.For more information go to http://bioperine.com/curcumin.htmlThus, by simply administering a capsule, you also benefit from the fantastic effects of pure curcumin, and the increase in its biovalidity, so that the active substance can reach the tissues.For additional information and orders, visit our website www.curcumin95.ro.Subscribe to Ziare.com notifications:To subscribe to Newspapers.Com notifications press the top button Allow or Allow1. 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